Odalasvir
Odalasvir (ACH-3102) is a potent and selective inhibitor of HCV NS5A, and can be used in research on hepatitis C virus infection.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1415119-52-6
- Formule: C60H72N8O6
- Masse moléculaire:1001.26
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1415119-52-6
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Masse moléculaire 1001.26
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Formule C60H72N8O6
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SMILES
COC(N[C@@H](C(C)C)C(N1[C@H](C2=NC3=CC=C(C4=CC5=CC=C4CCC6=CC=C(CC5)C(C7=CC=C(N=C([C@H]8N([C@]9([H])[C@](CCCC9)([H])C8)C([C@H](C(C)C)NC(OC)=O)=O)N%10)C%10=C7)=C6)C=C3N2)C[C@@]%11([H])[C@]1([H])CCCC%11)=O)=O
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Synonyms
ACH-3102; JNJ64289901
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Odalasvir Related Classifications
HY-124182 Related Classifications
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