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Cat. No.: HY-156032

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PIMPC

PIMPC is a compound with antioxidant and metal-chelating properties. PIMPC is a novel inhibitor of glycogen synthase kinase 3 (GSK-3). PIMPC has potential anti-Alzheimer's disease effect.

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CAS No.: 2250244-44-9
Formule: C₂₁H₁₉N₅O
Masse moléculaire:357.41

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

PIMPC Chemical Structure

CAS No.: 2250244-44-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

PIMPC is a compound with antioxidant and metal-chelating properties. PIMPC is a novel inhibitor of glycogen synthase kinase 3 (GSK-3). PIMPC has potential anti-Alzheimer's disease effect^[1].

Voir tous les produits spécifiques à Isoform GSK-3 :

Cellular Effect

Cell Line	Type	Value	Description	References
PC-12	IC₅₀	83.18 μM Compound: 9b	Cytotoxicity against rat PC12 cells measured after 24 hrs by MTT assay Cytotoxicity against rat PC12 cells measured after 24 hrs by MTT assay	[PMID: 30772605]
SH-SY5Y	IC₅₀	158.07 μM Compound: 9b	Cytotoxicity against human SH-SY5Y cells measured after 24 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells measured after 24 hrs by MTT assay	[PMID: 30772605]

Chemical Information

CAS No. 2250244-44-9
Masse moléculaire 357.41
Formule C₂₁H₁₉N₅O
SMILES

O=C(C1CC1)NC2=NC=CC(/C=N/C3=CC(C4=CC=CC=C4)=CN=C3N)=C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wu D, et al. A quantitative analysis method for a new glycogen synthase kinase-3 inhibitor and its pharmacokinetics in rats. Biomed Chromatogr. 2023 Aug;37(8):e5649. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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PIMPC

Voir tous les produits spécifiques à Isoform GSK-3

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

PIMPC Related Classifications

HY-156032 Related Classifications