PqsR-IN-2
PqsR-IN-2 (Compound 19) is a potent PqsR (Pseudomonas aeruginosa quorum sensing transcriptional regulator) inhibitor. PqsR-IN-1 attenuates pyocyanin production and has very low cytotoxicity.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2982271-63-4
- Formule: C18H20ClN3OS
- Masse moléculaire:361.89
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
PqsR[1]
PqsR-IN-2 (Compound 19) inhibits pqs system with IC50 values of 298 ± 182.0 nM and 265 ± 3.4 nM against two different PA strains PAO1-L and PA14, respectively[1].
PqsR-IN-2 significantly reduces pyocyanin production to 36% against a control of 0.1% DMSO at 3 × the IC50 value in P. aeruginosa strain PAO1-L[1].
PqsR-IN-2 (0-100 µM, 16 h) shows no significant toxicity to A549 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:A549 lung epithelial cells
-
Concentration:0.1, 1, 12.5, 25, 50, and 100 µM
-
Incubation Time:16 h
-
Result:Showed no significant toxicity.
Chemical Information
-
CAS No. 2982271-63-4
-
Masse moléculaire 361.89
-
Formule C18H20ClN3OS
-
SMILES
CCCCCCC1=NC(CN2C=NC3=CC=C(C=C3C2=O)Cl)=CS1
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PqsR-IN-2 Related Classifications
HY-146706 Related Classifications
Powered by Bioz