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Cat. No.: HY-111849

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Imatinib carbaldehyde

(Synonyms: CGP-57148B carbaldehyde; STI571 carbaldehyde; PROTAC ABL binding moiety 1)

Imatinib carbaldehyde (CGP-57148B carbaldehyde), the Imatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER.

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CAS No.: 1436868-85-7
Formule: C₂₉H₂₉N₇O₂
Masse moléculaire:507.59

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Imatinib carbaldehyde Chemical Structure

CAS No.: 1436868-85-7

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Fluorescent Dye

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Activité biologique

Description

Imatinib carbaldehyde (CGP-57148B carbaldehyde), the Imatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER^[1].

Chemical Information

CAS No. 1436868-85-7
Masse moléculaire 507.59
Formule C₂₉H₂₉N₇O₂
SMILES

CC1=CC=C(NC(C2=CC=C(CN3CCN(C=O)CC3)C=C2)=O)C=C1NC4=NC=CC(C5=CC=CN=C5)=N4
Synonyms

CGP-57148B carbaldehyde; STI571 carbaldehyde; PROTAC ABL binding moiety 1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666. [Content Brief]

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Imatinib carbaldehyde

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Chemical Information

Pureté et documentation

Références

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Imatinib carbaldehyde Related Classifications

HY-111849 Related Classifications