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RET-IN-22

RET-IN-22 (compound 17b) is a potent, selective and orally active RET inhibitor with an IC50 of 20.9 nM and 18.3 nM for wild-type RET and RET-V804M, respectively. RET-IN-22 shows highly selective profile to most kinases, especially to EGFR and VEGFR2. RET-IN-22 has anticancer effects.

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  • CAS No.: 2918281-79-3
  • Formule: C29H31F3N6O4
  • Masse moléculaire:584.59
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • RET-IN-22 Chemical Structure
    RET-IN-22 Chemical Structure
CAS No.: 2918281-79-3
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  • RET-IN-22 Chemical Structure
    RET-IN-22 Chemical Structure
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  • RET-IN-22