SDH-IN-15
SDH-IN-15 (Compound 5e) is an inhibitor of succinate dehydrogenase (SDH) (IC50=2.04 μM). SDH-IN-15 has significant antifungal activity. SDH-IN-15 blocks the mitochondrial respiratory chain of the fungus through inhibition of SDH, resulting in fungal death.
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- Formule: C21H19BrF2N4O2
- Masse moléculaire:477.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
SDH-IN-15 shows antifungal activity of EC50=0.039 μg/mL (R. solani); 0.426 μg/mL (S. sclerotiorum); and 3.482 μg/mL (B. cinerea), respectively. Superior to Boscalid (HY-119976) and Fluxapyroxad (HY-135549)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 477.30
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Formule C21H19BrF2N4O2
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SMILES
O=C(C1=CN(C)N=C1C(F)F)NC2=CC=CC=C2/C(C)=N/OCC3=CC=C(Br)C=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SDH-IN-15 Related Classifications
HY-158321 Related Classifications
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