STING agonist-31
STING agonist-31 is a STING agonist, with EC50 values of 0.24 and 39.51 μM for h-STING and m-STING. STING agonist-31 has antitumor efficiency.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2719001-44-0
- Formule: C43H51N15O6
- Masse moléculaire:873.96
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
STING agonist-31 (Compound 40) activates h-STING and m-STING with EC50 values of 0.24 and 39.51 μM[1].
STING agonist-31 (0-10 μM, 24 h) activates the ISG signaling and NF-κB signaling[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
STING agonist-31 (1 mg/kg, i.v., rats) shows T1/2: 0.697 h, AUClast: 678 h•ng/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Mice models bearing orthotopic transplanted breast tumor (4T1) or subcutaneous transplanted colon tumor (CT26)[1]
-
Dosage:10 mg/kg
-
Administration:i.v., at days 1, 4, and 7
-
Result:Inhibited tumor Growth.
Chemical Information
-
CAS No. 2719001-44-0
-
Masse moléculaire 873.96
-
Formule C43H51N15O6
-
SMILES
O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OCCCN4CCOCC4)=C3N2C/C=C/CN5C6=C(OC)C=C(C7=NN=CN7)C=C6N=C5NC(C8=CC(C)=NN8CC)=O
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
STING agonist-31 Related Classifications
HY-153546 Related Classifications
Powered by Bioz