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Cat. No.: HY-143979S

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1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d₄

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Based on 1 Customer Validation

trans-4’-Hydroxy CCNU Lomustine-d₄ is the deuterium labeled trans-4’-Hydroxy CCNU Lomustine.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Pureté: 99.0%
Formule: C₉H₁₂D₄ClN₃O₃
Masse moléculaire:253.72

Stockage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d₄ Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- Application
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

trans-4’-Hydroxy CCNU Lomustine-d₄ is the deuterium labeled trans-4’-Hydroxy CCNU Lomustine^[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 56239-24-8
Appearance Solid
Masse moléculaire 253.72
Formule C₉H₁₂D₄ClN₃O₃
Color White to off-white
SMILES

O=C(N[C@H]1CC[C@H](O)CC1)N(C([2H])([2H])C([2H])([2H])Cl)N=O
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d₄

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Activité biologique
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- In Vitro
- Application
Chemical Information
Pureté et documentation
Références

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1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4 Related Classifications

HY-143979S Related Classifications

1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d₄

1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d₄ Related Classifications