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Cat. No.: HY-156524

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USP1-IN-5

USP1-IN-5 (compound 10) is a USP1 inhibitor (IC₅₀<50 nM). USP1-IN-5 also inhibits MDA-MB-436 cells with IC₅₀ <50 nM.

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CAS No.: 2925547-94-8
Formule: C₂₇H₂₃F₃N₈O
Masse moléculaire:532.52

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

USP1-IN-5 Chemical Structure

CAS No.: 2925547-94-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

USP1-IN-5 (compound 10) is a USP1 inhibitor (IC₅₀<50 nM). USP1-IN-5 also inhibits MDA-MB-436 cells with IC₅₀ <50 nM^[1].

IC₅₀ & Target

IC50: <50 nM (USP1)^[1]

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Chemical Information

CAS No. 2925547-94-8
Masse moléculaire 532.52
Formule C₂₇H₂₃F₃N₈O
SMILES

FC(F)(C1=CN(C)C(C23C4C5C2C6C3C4C65CN7N=CC8=C7N=C(C9=C(C%10CC%10)N=CN=C9OC)N=C8)=N1)F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wu J, et al. Preparation of heteroaromatic compounds as small molecule inhibitors of ubiquitin specific protease 1 (USP1) and uses thereof. World Intellectual Property Organization, WO2023083285 A1. 2023-05-19.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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USP1-IN-5

Voir tous les produits spécifiques à Isoform Deubiquitinase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

USP1-IN-5 Related Classifications

HY-156524 Related Classifications