Carbobenzoxy-4-aminobutyric acid
Based on 1 Customer Validation
Carbobenzoxy-4-aminobutyric acid is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 5105-78-2
- Formula: C12H15NO4
- Molecular Weight:237.26
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E563 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 5105-78-2
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Appearance Solid
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Molecular Weight 237.26
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Formula C12H15NO4
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Color White to off-white
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SMILES
O=C(O)CCCNC(=O)OCC=1C=CC=CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (421.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2148 mL | 21.0739 mL | 42.1479 mL | 105.3696 mL |
| 5 mM | 0.8430 mL | 4.2148 mL | 8.4296 mL | 21.0739 mL | |
| 10 mM | 0.4215 mL | 2.1074 mL | 4.2148 mL | 10.5370 mL | |
| 15 mM | 0.2810 mL | 1.4049 mL | 2.8099 mL | 7.0246 mL | |
| 20 mM | 0.2107 mL | 1.0537 mL | 2.1074 mL | 5.2685 mL | |
| 25 mM | 0.1686 mL | 0.8430 mL | 1.6859 mL | 4.2148 mL | |
| 30 mM | 0.1405 mL | 0.7025 mL | 1.4049 mL | 3.5123 mL | |
| 40 mM | 0.1054 mL | 0.5268 mL | 1.0537 mL | 2.6342 mL | |
| 50 mM | 0.0843 mL | 0.4215 mL | 0.8430 mL | 2.1074 mL | |
| 60 mM | 0.0702 mL | 0.3512 mL | 0.7025 mL | 1.7562 mL | |
| 80 mM | 0.0527 mL | 0.2634 mL | 0.5268 mL | 1.3171 mL | |
| 100 mM | 0.0421 mL | 0.2107 mL | 0.4215 mL | 1.0537 mL |