Carboxyrhodamine 110-PEG4-alkyne

Cat. No.: HY-141089: Ficha de datos Instrucciones de manejo
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Carboxyrhodamine 110-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

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Carboxyrhodamine 110-PEG4-alkyne Estructura química

No. CAS : 2055103-66-5

Tamaño	Precio	Stock
1 mg		Pide un presupuesto y un plazo de entrega
5 mg		Pide un presupuesto y un plazo de entrega

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This product is a controlled substance and not for sale in your territory.

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

Carboxyrhodamine 110-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

587.62

Fòrmula

C₃₂H₃₃N₃O₈

No. CAS

2055103-66-5

SMILES

C#CCOCCOCCOCCOCCNC(C1=CC=C(C2=C3C=CC(N)=CC3=[O+]C4=C2C=CC(N)=C4)C(C([O-])=O)=C1)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]