1004537-75-0
Chemical Structure
Monasfluore A
- CAS No.: 1004537-75-0
- Formula:C21H24O5
- Molecular Weight:356.41
IUPAC Name: (6aS,9R,9aS)-9-hexanoyl-6a-methyl-3-((E)-prop-1-en-1-yl)-9,9a-dihydro-6H-furo[2,3-h]isochromene-6,8(6aH)-dione
InChIKey: NUJXNRMLMKAJSY-AHQOVFMLSA-N
SMILES: C[C@]12[C@]([C@@H](C(O2)=O)C(CCCCC)=O)([H])C3=COC(/C=C/C)=CC3=CC1=O
Biological Activity: Monasfluore A is an azaphenanthrenone derivative with antioxidant activity. Monasfluore A inhibits LPS-induced nitric oxide production. Monasfluore A scavenges DPPH and superoxide anion free radicals. Monasfluore A exerts cellular antioxidant activity in oxidatively damaged colon adenocarcinoma cells. Monasfluore A shows no antiproliferative effect on human laryngeal cancer cells and colon adenocarcinoma cells[1][2].
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Monasfluore A | Monasfluore A is an azaphenanthrenone derivative with antioxidant activity. Monasfluore A inhibits LPS-induced nitric oxide production. Monasfluore A scavenges DPPH and superoxide anion free radicals. Monasfluore A exerts cellular antioxidant activity in oxidatively damaged colon adenocarcinoma cells. Monasfluore A shows no antiproliferative effect on human laryngeal cancer cells and colon adenocarcinoma cells. | |||||||||||||||||||||
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References
- [1]. Hsu YW, et al. New anti-inflammatory and anti-proliferative constituents from fermented red mold rice Monascus purpureus NTU 568. Molecules. 2010;15(11):7815-7824. Published 2010 Nov 3. [Content Brief]
- [2]. Wu L, et al. Comparative Study on the Antioxidant Activity of Monascus Yellow Pigments From Two Different Types of Hongqu-Functional Qu and Coloring Qu. Front Microbiol. 2021 Aug 2;12:715295. [Content Brief]
