1013933-37-3
1013933-37-3
Chemical Structure
CP 376395 hydrochloride
- CAS No.: 1013933-37-3
- Formula:C21H31ClN2O
- Molecular Weight:362.94
IUPAC Name: 2-(mesityloxy)-3,6-dimethyl-N-(pentan-3-yl)pyridin-4-amine hydrochloride
InChIKey: UDIOZDHQQNYISB-UHFFFAOYSA-N
SMILES: CC1=C(OC2=NC(C)=CC(NC(CC)CC)=C2C)C(C)=CC(C)=C1.[H]Cl
Biological Activity: CP 376395 hydrochloride is a potent, selective, and brain-penetrable Corticotropin releasing factor 1 (CRF1) receptor antagonist[1][2].
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CP 376395 hydrochloride | CP 376395 hydrochloride is a potent, selective, and brain-penetrable Corticotropin releasing factor 1 (CRF1) receptor antagonist. | |||||||||||||||||||||
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References
- [1]. Chen YL, et al. 2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists. J Med Chem. 2008 Mar 13;51(5):1385-92. [Content Brief]
- [2]. Giardino WJ, et al. CRF1 receptor signaling regulates food and fluid intake in the drinking-in-the-dark model of binge alcohol consumption. Alcohol Clin Exp Res. 2013 Jul;37(7):1161-70. [Content Brief]
Keywords
