1027786-12-4
Chemical Structure
QR-0217
- CAS No.: 1027786-12-4
- Formula:C19H13NO3
- Molecular Weight:303.31
IUPAC Name: 3-(6-hydroxynaphthalen-2-yl)-1H-indole-5-carboxylic acid
InChIKey: OPTWFLWYDUFHPL-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(NC=C2C3=CC=C4C=C(O)C=CC4=C3)C=C1)O
Biological Activity: QR-0217 is a potent Aβ1-40 aggregation inhibitor with an IC50 value of 7.5 µM. QR-0217 inhibits α-synuclein aggregation. QR-0217 reduces memory impairments caused by Aβ neurotoxicity[1].
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QR-0217 | 98.47% | QR-0217 is a potent Aβ1-40 aggregation inhibitor with an IC50 value of 7.5 µM. QR-0217 inhibits α-synuclein aggregation. QR-0217 reduces memory impairments caused by Aβ neurotoxicity. | ||||||||||||||||||||
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Keywords