1029317-21-2
1029317-21-2
Chemical Structure
PF-4191834
Synonym(s): PF-04191834
- CAS No.: 1029317-21-2
- Formula:C22H23N3O2S
- Molecular Weight:393.50
IUPAC Name: 4-(3-((4-(1-methyl-1H-pyrazol-5-yl)phenyl)thio)phenyl)tetrahydro-2H-pyran-4-carboxamide
InChIKey: DVNQWYLVSNPCJZ-UHFFFAOYSA-N
SMILES: O=C(C1(C2=CC=CC(SC3=CC=C(C4=CC=NN4C)C=C3)=C2)CCOCC1)N
Biological Activity: PF-4191834 (PF-04191834) is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) (IC50=229 nM), displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes, and is effective in inflammation and pain[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-4191834 | 99.69% | PF-4191834 (PF-04191834) is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) (IC50=229 nM), displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes, and is effective in inflammation and pain. | ||||||||||||||||||||
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