103221-88-1
Chemical Structure
BW A575C
- CAS No.: 103221-88-1
- Formula:C29H43N5O8
- Molecular Weight:589.68
IUPAC Name: (1-carboxy-5-(4-(2-hydroxy-3-(isopropylamino)propoxy)-1H-indole-2-carboxamido)pentyl)alanyl-L-proline
InChIKey: XCLLRLKRCYZTES-PBKHYBTFSA-N
SMILES: CC(C)NCC(O)COC1=C2C(NC(C(NCCCCC(C(O)=O)NC(C)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=C2)=CC=C1
Biological Activity: BW A575C is a dual inhibitor against angiotensin converting enzyme (ACE) and β-adrenoceptor. BW A575C produces a competitive blockade of Isoprenaline (HY-108353)-induced tachycardia in a guinea-pig right atrial. BW A575C also inhibits Angiotensin I (HY-P1032)-induced pressor responses in rats. BW A575C is promising for research of hypertensive diseases[1].
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BW A575C | BW A575C is a dual inhibitor against angiotensin converting enzyme (ACE) and β-adrenoceptor. BW A575C produces a competitive blockade of Isoprenaline (HY-108353)-induced tachycardia in a guinea-pig right atrial. BW A575C also inhibits Angiotensin I (HY-P1032)-induced pressor responses in rats. BW A575C is promising for research of hypertensive diseases. | |||||||||||||||||||||
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Keywords
