104340-86-5
104340-86-5
Chemical Structure
Leminoprazole
Synonym(s): NC 1300O3
- CAS No.: 104340-86-5
- Formula:C19H23N3OS
- Molecular Weight:341.47
IUPAC Name: 2-(((1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-N-isobutyl-N-methylaniline
InChIKey: PSIREIZGKQBEEO-UHFFFAOYSA-N
SMILES: CC(CN(C1=C(CS(C2=NC3=C(N2)C=CC=C3)=O)C=CC=C1)C)C
Biological Activity: Leminoprazole (NC 1300O3) is an inhibitor for acid pump, H+ K+-ATPase,. Leminoprazole stimulates the secretion and synthesis of gastric mucus, attenuates gastric ulcers. Leminoprazole is orally active[1][2][3].
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Leminoprazole | Leminoprazole (NC 1300O3) is an inhibitor for acid pump, H+ K+-ATPase,. Leminoprazole stimulates the secretion and synthesis of gastric mucus, attenuates gastric ulcers. Leminoprazole is orally active. | |||||||||||||||||||||
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References
- [1]. Masuda M, et al., [Studies on the inhibitory action of leminoprazole against rabbit gastric H+,K(+)-ATPase]. Nihon Yakurigaku Zasshi. 1994 Oct;104(4):325-35. Japanese. [Content Brief]
- [2]. Saito E, et al., Inhibitory effect of leminoprazole on acid secretion in parietal cells isolated from guinea pig gastric mucosa. Jpn J Pharmacol. 1995 May;68(1):19-23. [Content Brief]
- [3]. Takahashi S, et al., Mechanism by which orally administered leminoprazole stimulates mucus synthesis in rats. Pharmacology. 1998 Jul;57(1):47-56. [Content Brief]
