105080-50-0
Chemical Structure
ICI-200880
- CAS No.: 105080-50-0
- Formula:C30H34ClF3N4O7S
- Molecular Weight:687.13
IUPAC Name: N1-((4-chlorophenyl)sulfonyl)-N4-((2S)-3-methyl-1-oxo-1-((2S)-2-((1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)carbamoyl)pyrrolidin-1-yl)butan-2-yl)terephthalamide
InChIKey: YGPYJEFIYYPEEE-OTKIHZFJSA-N
SMILES: O=C(C1=CC=C(C(NS(=O)(C2=CC=C(Cl)C=C2)=O)=O)C=C1)N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(NC(C(C)C)C(C(F)(F)F)=O)=O)=O
Biological Activity: ICI-200880 is a potent, selective and reversible human neutrophil elastase (HNE) inhibitor. ICI-200880 is promising for research of inflammatory lung diseases related to neutrophil elastase, such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF)[1].
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ICI-200880 | ICI-200880 is a potent, selective and reversible human neutrophil elastase (HNE) inhibitor. ICI-200880 is promising for research of inflammatory lung diseases related to neutrophil elastase, such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). | |||||||||||||||||||||
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