1058-61-3
Chemical Structure
β-Sitostenone
Synonym(s): Δ4-Sitosterol-3-one; β-Rosasterol oxide
- CAS No.: 1058-61-3
- Formula:C29H48O
- Molecular Weight:412.69
IUPAC Name: (8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: RUVUHIUYGJBLGI-XJZKHKOHSA-N
SMILES: C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC[C@@H](CC)C(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(CC3)=CC(CC4)=O)C
Biological Activity: β-Sitostenone (Δ4-Sitosterol-3-one; β-Rosasterol oxide) is a sterol isolated from Cleistanthus eberhardtii. β-Sitostenone inhibits tyrosinase (tyrosinase) and cyclooxygenase (COX-1 and COX-2). β-Sitostenone has potential anti-melanogenic, anticancer, and anti-inflammatory activities. β-Sitostenone can be used in research on inflammation, cancer, and cosmetics[1][2][3][4][5][6][7][8][9].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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β-Sitostenone | 95.0% | β-Sitostenone (Δ4-Sitosterol-3-one; β-Rosasterol oxide) is a sterol isolated from Cleistanthus eberhardtii. β-Sitostenone inhibits tyrosinase (tyrosinase) and cyclooxygenase (COX-1 and COX-2). β-Sitostenone has potential anti-melanogenic, anticancer, and anti-inflammatory activities. β-Sitostenone can be used in research on inflammation, cancer, and cosmetics. | ||||||||||||||||||||
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References
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- [2]. Hong NL, et al. CHEMICAL CONSTITUENTS FROM THE STEMS OF CLEISTANTHUS EBERHARDTII. Tạp chí Dược liệu. 2025;30(2):74-9.
- [3]. Hernández-Hernández AB, et al. Biological properties and chemical composition of Jatropha neopauciflora Pax. African journal of traditional, complementary and alternative medicines. 2017 Feb 20;14(1):32-42.
- [4]. Ariefin M, et al. Phytochemical Analysis and Study of Molecular Docking of Leucaena leucocephala Leave Extract as Anticancer. Stannum: Jurnal Sains dan Terapan Kimia. 2024 May 1;6(1):1-9.
- [5]. Duborija-Kovacevic N, et al. Kidney, skeletal muscle and myocardium as potential target sites of Pygeum africanum toxicity in Wistar rats. Rev Int Androl. 2019 Jan-Mar;17(1):8-14.
- [6]. Sinan KI, et al. Evaluation of Pharmacological and Phytochemical Profiles of Piptadeniastrum africanum (Hook.f.) Brenan Stem Bark Extracts. Biomolecules. 2020;10(4):516.
- [7]. Tsao DA, et al. Anticancer Activity of Metabolites of Coix lachrymal-jobi and Its Effect on Growth Inhibition in Cancer Cells. Chemistry of Natural Compounds. 2026 Aug 10:1-4.
- [8]. Okwute SK, et al. Chemical constituents, antimicrobial and termite repellent activities of Commiphora africana (Caesalpiniaceae) root extracts. ChemSearch Journal. 2022 Aug 9;13(1):184-90.
- [9]. Islam M, et al. Phyto-pharmacological Investigations of Leaves of Cissus trifoliata (L.). Dhaka Univ J Pharm Sci. 2022;21(1):69-75.
