106224-67-3
106224-67-3
Chemical Structure
NC-182
- CAS No.: 106224-67-3
- Formula:C24H24N4O5
- Molecular Weight:448.47
IUPAC Name: methyl 6-((2-(dimethylamino)ethyl)carbamoyl)-5-hydroxy-10-methoxybenzo[a]phenazine-9-carboxylate
InChIKey: DGSXFRJEHFETBL-UHFFFAOYSA-N
SMILES: O=C(OC)C1=CC2=NC3=C(C(O)=C4C(C=CC=C4)=C3N=C2C=C1OC)C(NCCN(C)C)=O
Biological Activity: NC-182 is an anti-tumor agent and DNA intercalator with a preference for B-form DNA. NC-182 can also promote the unwinding of Z-form DNA to B-form. NC-182 has a potent inhibitory effect on multidrug-resistant and sensitive tumors.
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NC-182 | NC-182 is an anti-tumor agent and DNA intercalator with a preference for B-form DNA. NC-182 can also promote the unwinding of Z-form DNA to B-form. NC-182 has a potent inhibitory effect on multidrug-resistant and sensitive tumors. | |||||||||||||||||||||
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Keywords
