107889-32-7
107889-32-7
Chemical Structure
LY 178002
- CAS No.: 107889-32-7
- Formula:C18H25NO2S
- Molecular Weight:319.46
IUPAC Name: (E)-5-(3,5-di-tert-butyl-4-hydroxybenzylidene)thiazolidin-4-one
InChIKey: BUDGLLLMROWLOB-NTEUORMPSA-N
SMILES: O=C1NCS/C1=C/C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2
Biological Activity: LY 178002 is a potent inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2, with IC50 of 0.6 μM for 5-lipoxygenase, inhibits cellular production of LTB4 by human polymorphonuclear leukocytes, and shows relatively weak inhibition on cyclooxygenase.
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LY 178002 | 99.60% | LY 178002 is a potent inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2, with IC50 of 0.6 μM for 5-lipoxygenase, inhibits cellular production of LTB4 by human polymorphonuclear leukocytes, and shows relatively weak inhibition on cyclooxygenase. | ||||||||||||||||||||
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