1111287-26-3
1111287-26-3
Chemical Structure
INK4C-IN-3
- CAS No.: 1111287-26-3
- Formula:C19H16N2O4
- Molecular Weight:336.34
IUPAC Name: 4-acetamido-N-(4-methyl-2-oxo-2H-chromen-7-yl)benzamide
InChIKey: FVHODORGQJKWTM-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C=C1)NC(C)=O)NC2=CC(OC3=O)=C(C(C)=C3)C=C2
Biological Activity: INK4C-IN-3 is a synthetic coumarin amide compound and a small-molecule inhibitor of INK4C (p18INK4C). INK4C-IN-3 promotes the ex vivo expansion of human and mouse hematopoietic stem cells. INK4C-IN-3 can be used in research related to hematopoietic stem cell expansion[1][2].
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INK4C-IN-3 | INK4C-IN-3 is a synthetic coumarin amide compound and a small-molecule inhibitor of INK4C (p18INK4C). INK4C-IN-3 promotes the ex vivo expansion of human and mouse hematopoietic stem cells. INK4C-IN-3 can be used in research related to hematopoietic stem cell expansion. | |||||||||||||||||||||
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References
- [1]. Ronad PM, et al. Synthesis and evaluation of anti-inflammatory and analgesic activities of a novel series of substituted-N-(4-methyl-2-oxo-2H-chromen-7-yl) benzamides. Arzneimittelforschung. 2008;58(12):641-6. [Content Brief]
- [2]. Xie XQ, et al. Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Scientific reports. 2015 Dec 18;5:18115. [Content Brief]
