113170-86-8
Chemical Structure
Lamotrigine isethionate
Synonym(s): LTG isethionate; BW430C isethionate
- CAS No.: 113170-86-8
- Formula:C11H13Cl2N5O4S
- Molecular Weight:382.22
IUPAC Name: 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine 2-hydroxyethane-1-sulfonate
InChIKey: CJIDZLNMKONKAD-UHFFFAOYSA-N
SMILES: O=S(O)(CCO)=O.ClC1=C(Cl)C(C2=C(N)N=C(N)N=N2)=CC=C1
Biological Activity: Lamotrigine (BW430C) isethionate is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine isethionate selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine isethionate can be used for the research of epilepsy, focal seizure, et al[1][2].
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Lamotrigine isethionate | Lamotrigine (BW430C) isethionate is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine isethionate selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine isethionate can be used for the research of epilepsy, focal seizure, et al. | |||||||||||||||||||||
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- [1]. M J Leach, et al. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. Sep-Oct 1986;27(5):490-7. [Content Brief]
- [2]. Damianka P Getova, et al. A study of the effects of lamotrigine on mice using two convulsive tests. Folia Med (Plovdiv). Apr-Jun 2011;53(2):57-62. [Content Brief]
Keywords
