1131996-12-7
Chemical Structure
Apixaban-d3
Synonym(s): BMS-562247-01-d3
- CAS No.: 1131996-12-7
- Formula:C25H22D3N5O4
- Molecular Weight:462.52
IUPAC Name: 2-((S)-3-(((S)-1-ethoxy-1-oxo-4-(phenyl-d5)butan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid
InChIKey: QNZCBYKSOIHPEH-FIBGUPNXSA-N
SMILES: O=C1C2=C(CCN1C3=CC=C(N4C(CCCC4)=O)C=C3)C(C(N)=O)=NN2C5=CC=C(C=C5)OC([2H])([2H])[2H]
Biological Activity: Apixaban-d3 (BMS-562247-01-d3) is the deuterium labeled Apixaban (HY-50667)[1]. Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Kis of 0.08 nM and 0.17 nM in human and rabbit, respectively[2]. Apixaban is in development for the prevention and treatment of various thromboembolic diseases[3].
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Apixaban-d3 | 99.9% | Apixaban-d3 (BMS-562247-01-d3) is the deuterium labeled Apixaban (HY-50667). Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Kis of 0.08 nM and 0.17 nM in human and rabbit, respectively. Apixaban is in development for the prevention and treatment of various thromboembolic diseases. | ||||||||||||||||||||
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Apixaban (Standard) | 99.95% | Apixaban (Standard) is the analytical standard of Apixaban. This product is intended for research and analytical applications. Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. Apixaban is in development for the prevention and treatment of various thromboembolic diseases. | ||||||||||||||||||||
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Apixaban-13C,d3 | 97.11% | Apixaban-13C,d3 (BMS-562247-01-13C,d3) is a deuterium and 13C labeled Apixaban (HY-50667). Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. | ||||||||||||||||||||
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Apixaban | 99.99% | Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. Apixaban is in development for the prevention and treatment of various thromboembolic diseases. | ||||||||||||||||||||
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Similarity Score 0.91
HY-I0459SApixaban acid-13C,d3 -
Similarity Score 0.91
HY-100655O-Desmethyl apixaban -
Similarity Score 0.91
HY-I0459Apixaban impurity 41 -
Similarity Score 0.90
HY-Z4088Apixaban impurity 10 -
Similarity Score 0.89
![1-(4-Chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide Chemical Structure](//file.medchemexpress.com/product_pic/hy-i0462.gif)
HY-I04621-(4-Chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide -
Similarity Score 0.89
HY-100652O-Desmethyl apixaban sulfate -
Similarity Score 0.88
HY-I04655''-Methyl-apixaban -
Similarity Score 0.88
HY-I0460Apixaban impurity 47 -
Similarity Score 0.87
HY-I0464Apixaban impurity 3 -
Explore the MedChemAI to find more analogs
![1-(4-Chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide Chemical Structure](http://file.medchemexpress.com/product_pic/hy-i0462.gif)
