114773-44-3
Chemical Structure
EXP-6803
- CAS No.: 114773-44-3
- Formula:C25H25ClN3NaO5
- Molecular Weight:505.93
IUPAC Name: sodium 2-((4-((2-butyl-4-chloro-5-(2-methoxy-2-oxoethyl)-1H-imidazol-1-yl)methyl)phenyl)carbamoyl)benzoate
InChIKey: QPMLWMFMSLFKBS-UHFFFAOYSA-M
SMILES: O=C(C(C=CC=C1)=C1C(O[Na])=O)NC(C=C2)=CC=C2CN3C(CC(OC)=O)=C(N=C3CCCC)Cl
Biological Activity: EXP-6803 is a specific nonpeptide angiotensin II receptor antagonist with antihypertensive activity. EXP-6803 inhibits the contractile response to angiotensin II with a pA2 value of 7.20. EXP-6803 effectively blocks responses to angiotensin I and II while not affecting responses to bradykinin or acetylcholine in guinea pig ileum. EXP-6803 can be used for hypertension research[1].
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EXP-6803 | EXP-6803 is a specific nonpeptide angiotensin II receptor antagonist with antihypertensive activity. EXP-6803 inhibits the contractile response to angiotensin II with a pA2 value of 7.20. EXP-6803 effectively blocks responses to angiotensin I and II while not affecting responses to bradykinin or acetylcholine in guinea pig ileum. EXP-6803 can be used for hypertension research. | |||||||||||||||||||||
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