1160426-89-0
Chemical Structure
GSK2181236A
- CAS. Nr.: 1160426-89-0
- Formula:C31H21F6N3O4
- Molecular Weight:613.51
IUPAC Name: 1-(6-(2-((3-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)methoxy)phenyl)pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
InChIKey: YNDMDCJWXXDPFE-UHFFFAOYSA-N
SMILES: O=C(C1=C(C(F)(F)F)N(C2=NC(C3=CC=CC=C3OCC4=CC=C(C5=CC=C(OC(F)(F)F)C=C5)C=C4C)=CC=C2)N=C1)O
Biological Activity: GSK2181236A is a NO-insensitive soluble guanylate cyclase (sGC) activator. GSK2181236A can dilate blood vessels, decrease mean arterial pressure and attenuate the development of cardiac hypertrophy. GSK2181236A can be used for the research of cardiovascular disease, such as hypertension[1].
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GSK2181236A | GSK2181236A is a NO-insensitive soluble guanylate cyclase (sGC) activator. GSK2181236A can dilate blood vessels, decrease mean arterial pressure and attenuate the development of cardiac hypertrophy. GSK2181236A can be used for the research of cardiovascular disease, such as hypertension. | |||||||||||||||||||||
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