1190217-35-6
1190217-35-6
Chemical Structure
ASP7663
- CAS. Nr.: 1190217-35-6
- Formula:C14H14FNO3
- Molecular Weight:263.26
IUPAC Name: (E)-2-(7-fluoro-1-isobutyl-2-oxoindolin-3-ylidene)acetic acid
InChIKey: RCVZUIGCNAAMIC-UXBLZVDNSA-N
SMILES: O=C(O)/C=C1C(N(CC(C)C)C2=C/1C=CC=C2F)=O
Biological Activity: ASP7663 is an orally active and selective TRPA1 agonist. ASP7663 exerts both anti-constipation and anti-abdominal pain actions[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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ASP7663 | 99.26% | ASP7663 is an orally active and selective TRPA1 agonist. ASP7663 exerts both anti-constipation and anti-abdominal pain actions. | ||||||||||||||||||||
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ASP7663 (Standard) | ≥98% | ASP7663 (Standard) is the analytical standard of ASP7663 (HY-101907). This product is intended for research and analytical applications. ASP7663 is an orally active and selective TRPA1 agonist. ASP7663 exerts both anti-constipation and anti-abdominal pain actions. | ||||||||||||||||||||
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References
- [1]. Ryosuke Kojima, et al. Effects of Novel TRPA1 Receptor Agonist ASP7663 in Models of Drug-Induced Constipation and Visceral Pain. Eur J Pharmacol. 2014 Jan 15;723:288-93. [Content Brief]
- [2]. Yao Lu, et al. Transient Receptor Potential Ankyrin 1 Activation Within the Cardiac Myocyte Limits Ischemia-reperfusion Injury in Rodents. Anesthesiology. 2016 Dec;125(6):1171-1180. [Content Brief]
