1202764-07-5
1202764-07-5
Chemical Structure
AMG28
- CAS No.: 1202764-07-5
- Formula:C20H20N4O
- Molecular Weight:332.40
InChIKey: DGLFSNZWRYADFC-UHFFFAOYSA-N
SMILES: CC(C)(O)C#CC1=CC2=C(NC3=C2C4=C(C=NC(N)=N4)CCC3)C=C1
Biological Activity: AMG28 is an ATP-competitive inhibitor targeting TTBK1 and TTBK2, with IC50 values of 805 nM and 988 nM, respectively. AMG28 inhibits the phosphorylation of tau protein at the Ser422 site[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AMG28 | 99.74% | AMG28 is an ATP-competitive inhibitor targeting TTBK1 and TTBK2, with IC50 values of 805 nM and 988 nM, respectively. AMG28 inhibits the phosphorylation of tau protein at the Ser422 site. | ||||||||||||||||||||
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References
Keywords
