1204401-49-9
1204401-49-9
Chemical Structure
σ1 Receptor antagonist-1
- CAS No.: 1204401-49-9
- Formula:C21H23NOS
- Molecular Weight:337.48
IUPAC Name: 2-(1-benzylpiperidin-4-yl)thiochroman-4-one
InChIKey: XWMHOCDNGHEUMF-UHFFFAOYSA-N
SMILES: O=C1CC(C2CCN(CC3=CC=CC=C3)CC2)SC4=CC=CC=C41
Biological Activity: σ1 Receptor antagonist-1 is a highly potent and selective sigma 1 receptor antagonist (pKi=10.28). σ1 Receptor antagonist-1 inhibits cell growth, arrests cell cycle at G0/G1 phase and induces apoptosis of MCF-7/ADR cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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σ1 Receptor antagonist-1 | 99.89% | σ1 Receptor antagonist-1 is a highly potent and selective sigma 1 receptor antagonist (pKi=10.28). σ1 Receptor antagonist-1 inhibits cell growth, arrests cell cycle at G0/G1 phase and induces apoptosis of MCF-7/ADR cells. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.59
HY-180296AChE-IN-103 -
Similarity Score 0.57
HY-105545Dexetimide -
Similarity Score 0.57
HY-105545ALevetimide -
Similarity Score 0.56
HY-105545CDexetimide hydrochloride -
Similarity Score 0.56
HY-B1547ARBenzetimide hydrochloride (Standard) -
Similarity Score 0.56
HY-Z14380Donepezil impurity 16 -
Similarity Score 0.55
HY-100155R4-IBP (Standard) -
Similarity Score 0.55
HY-168826N-(1-Benzyl-4-piperidyl)-N-benzylpropanamide hydrochloride -
Similarity Score 0.54
HY-1339256-O-Desmethyl donepezil -
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