Dexetimide hydrochloride
Dexetimide hydrochloride ((+)-Benzetimide hydrochloride) is an antimuscarinic drug with the activity of suppressing neuroleptic-induced Parkinson's syndrome. Dexetimide hydrochloride is used to improve the symptoms of movement disorders caused by the use of neuroleptics. Dexetimide hydrochloride, as the (-)-enantiomer of (-)-Benzetimide, shows the ability to selectively inhibit cholinergic receptors.
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- CAS No.: 21888-96-0
- Formule: C23H27ClN2O2
- Masse moléculaire:398.93
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Chemical Information
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CAS No. 21888-96-0
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Masse moléculaire 398.93
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Formule C23H27ClN2O2
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SMILES
O=C1[C@@](C2CCN(CC2)CC3=CC=CC=C3)(C4=CC=CC=C4)CCC(N1)=O.Cl
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Synonyms
(+)-Benzetimide hydrochloride; (S)-(+)-Dexetimide hydrochloride; Dexbenzetimide hydrochloride
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Speck AL, et al. The absolute configuration and crystal structure of the anticholinergic drug dexbenzetimide. Nature. 1971 Aug 20;232(5312):575-6. [Content Brief]
[2]. Dexetimide: an effective drug for the control of extrapyramidal symptoms induced by pipothiazine palmitate [Content Brief]
[3]. Müller-Gärtner HW, et al. Imaging muscarinic cholinergic receptors in human brain in vivo with Spect, [123I]4-iododexetimide, and [123I]4-iodolevetimide. J Cereb Blood Flow Metab. 1992 Jul;12(4):562-70. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dexetimide hydrochloride Related Classifications
HY-105545C Related Classifications
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