12092-47-6
![[Rh(cod)Cl]2 Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-y1094.gif "[Rh(cod)Cl]2 Chemical Structure")
Chemical Structure
[Rh(cod)Cl]2
Synonym(s): Chloro(1,5-cyclooctadiene)rhodium(I) dimer
- CAS. Nr.: 12092-47-6
- Formula:C16H24Cl2Rh2
- Molecular Weight:493.08
InChIKey: PDJQCHVMABBNQW-MIXQCLKLSA-N
SMILES: C1=C\CC/C=C\CC/1.C2/C=C\CC/C=C\C2.[Rh]3[ClH][Rh][ClH]3
Biological Activity: [Rh(cod)Cl]2 (Chloro (1,5-cyclooctadiene) rhodium (I) dimer) is an organometallic rhodium (I) dimer precursor and platelet aggregation inhibitor. [Rh(cod)Cl]2 inhibits PAF-induced aggregation in washed rabbit platelets. [Rh(cod)Cl]2 inhibits aggregation induced by PAF, Thrombin, ADP and Collagen in human platelet-rich plasma. [Rh(cod)Cl]2 acts as a catalyst precursor for the hydrogenation of aromatic hydrocarbons, phenols, olefins and BINOL derivatives. [Rh(cod)Cl]2 is used in the research of cardiovascular diseases such as thromboinflammation-related disorders, tumor metastasis and atherosclerosis[1][2].
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[Rh(cod)Cl]2 | 99.91% | [Rh(cod)Cl]2 (Chloro (1,5-cyclooctadiene) rhodium (I) dimer) is an organometallic rhodium (I) dimer precursor and platelet aggregation inhibitor. [Rh(cod)Cl]2 inhibits PAF-induced aggregation in washed rabbit platelets. [Rh(cod)Cl]2 inhibits aggregation induced by PAF, Thrombin, ADP and Collagen in human platelet-rich plasma. [Rh(cod)Cl]2 acts as a catalyst precursor for the hydrogenation of aromatic hydrocarbons, phenols, olefins and BINOL derivatives. [Rh(cod)Cl]2 is used in the research of cardiovascular diseases such as thromboinflammation-related disorders, tumor metastasis and atherosclerosis. | ||||||||||||||||||||
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- [1]. Kalampalidis A, et al. Antithrombotic and antiplatelet activity of an organometallic rhodium (I) complex incorporating a substituted thieno‐[2, 3‐d]‐pyrimidine ligand: Synthesis, structural characterization, and molecular docking calculations. Applied Organometallic Chemistry. 2021 Jun;35(6):e6210.
- [2]. Wang DW, et al. A simple and highly effective method for hydrogenation of arenes by [Rh (COD) Cl] 2. Tetrahedron Letters. 2009 Mar 25;50(12):1282-5.
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