1217344-74-5
Chemical Structure
Vitronectin (367-378)
- CAS No.: 1217344-74-5
- Formula:C70H122N32O16
- Molecular Weight:1667.92
InChIKey: SAXSNZNBEWVSJE-LFOOZZFTSA-N
SMILES: NCCCC[C@H](NC(CN)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(NCC(O)=O)=O)=O)=O)=O)=O)CC2=CN=CN2)=O)=O)=O)=O)=O)=O
Biological Activity: Vitronectin (367-378) corresponds to the 367-378 residue fragment of Vitronectin and is a heparin/glycosaminoglycan-binding peptide. Vitronectin (367-378) acts on cell surface glycosaminoglycans and does not directly bind integrins. Vitronectin (367-378) supports pluripotent stem cell adhesion, proliferation, long-term self-renewal, pluripotency markers, normal karyotype, and undifferentiated culture. Vitronectin (367-378) facilitates the differentiation of human pluripotent stem cells into definitive endoderm and mesoderm. Vitronectin (367-378) can be used in research related to stem cell fate regulation[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Vitronectin (367-378) | 99.02% | Vitronectin (367-378) corresponds to the 367-378 residue fragment of Vitronectin and is a heparin/glycosaminoglycan-binding peptide. Vitronectin (367-378) acts on cell surface glycosaminoglycans and does not directly bind integrins. Vitronectin (367-378) supports pluripotent stem cell adhesion, proliferation, long-term self-renewal, pluripotency markers, normal karyotype, and undifferentiated culture. Vitronectin (367-378) facilitates the differentiation of human pluripotent stem cells into definitive endoderm and mesoderm. Vitronectin (367-378) can be used in research related to stem cell fate regulation. | ||||||||||||||||||||
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References
- [1]. Wrighton PJ, et al. Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins. Proceedings of the National Academy of Sciences of the United States of America. 2014 Dec 23;111(51):18126-31.
- [2]. Klim JR, et al. A defined glycosaminoglycan-binding substratum for human pluripotent stem cells. Nature methods. 2010 Dec;7(12):989-94.
- [3]. Ross A M, et al. Synthetic substrates for long-term stem cell culture. Polymer. 2012;53(13):2533-2539.
