122547-49-3
122547-49-3
Chemical Structure
Faropenem sodium
- CAS No.: 122547-49-3
- Formula:C12H14NNaO5S
- Molecular Weight:307.30
IUPAC Name: sodium (5R,6S)-6-((R)-1-hydroxyethyl)-7-oxo-3-((R)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
InChIKey: ICSAXRANXQSPQP-VUKDEKJYSA-M
SMILES: O=C([C@@]([H])1[C@@H](C)O)N([C@@H]1S2)C(C(O[Na])=O)=C2[C@@H]3OCCC3
Biological Activity: Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Faropenem sodium | 99.74% | Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Faropenem sodium (Standard) | ≥98% | Faropenem sodium (Standard) is the analytical standard of Faropenem sodium. This product is intended for research and analytical applications. Faropenem sodium is an orally bioavailable penem antibiotic which can efficiently kill Mycobacterium tuberculosis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Faropenem-d7 sodium | Faropenem-d7 sodium is the deuterium labeled Faropenem sodium (HY-76260). Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.88
HY-A0035Faropenem -
Similarity Score 0.68
HY-10004Faropenem daloxate -
Similarity Score 0.65
HY-105284ASulopenem sodium -
Similarity Score 0.63
HY-106791CGP 31608 -
Similarity Score 0.60
HY-111019ASCH 34343 sodium -
Similarity Score 0.60
HY-105284Sulopenem -
Similarity Score 0.59
HY-106922ASanfetrinem sodium -
Similarity Score 0.58
HY-119280Sch 29482 -
Explore the MedChemAI to find more analogs
References
- [1]. Dhar N, et al. Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic. Antimicrob Agents Chemother. 2015 Feb;59(2):1308-19. [Content Brief]
- [2]. Uchino H, et al. Faropenem transport across the renal epithelial luminal membrane via inorganic phosphate transporter Npt1. Antimicrob Agents Chemother. 2000 Mar;44(3):574-7. [Content Brief]
