1227638-29-0
1227638-29-0
Chemical Structure
Pirepemat
Synonym(s): IRL752
- CAS No.: 1227638-29-0
- Formula:C11H13F2NO
- Molecular Weight:213.22
IUPAC Name: (S)-3-(2,3-difluorophenyl)-3-methoxypyrrolidine
InChIKey: LJNFYMMXCXGFCP-LLVKDONJSA-N
SMILES: CO[C@]1(C(C=CC=C2F)=C2F)CCNC1
Biological Activity: Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson's disease[1][2]. IRL752 is a selective enhancer of cortical dopamine, acetylcholine and norepinephrine[3].
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Pirepemat | Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson's disease. IRL752 is a selective enhancer of cortical dopamine, acetylcholine and norepinephrine. | |||||||||||||||||||||
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References
- [1]. Systematic review of pharmacological interventions for people with Lewy body dementia
- [2]. Ipsen and IRLAB Enter Exclusive Worldwide Licensing Agreement Aimed to Improve the Lives of People Living with Parkinson's Disease.
- [3]. S Hjorth, et al. (3 S)-3-(2,3-difluorophenyl)-3-methoxypyrrolidine (IRL752) -a Novel Cortical-Preferring Catecholamine Transmission- and Cognition-Promoting Agent. J Pharmacol Exp Ther. 2020 Sep;374(3):404-419. [Content Brief]
