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Pirepemat (Synonyms: IRL752)

Cat. No.: HY-137447
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Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson's disease.

For research use only. We do not sell to patients.

Pirepemat Chemical Structure

Pirepemat Chemical Structure

CAS No. : 1227638-29-0

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Description

Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson's disease[1][2].

In Vitro

IRL752 displayed its highest in vitro affinities for 5-HT and NA-related targets[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

IRL752 (3.7-100 µmol/kg, s.c.) has no significant effect on acute hyper-dopaminergic or hypo-glutamatergic motor responses, but reversed deficits resulting from hypomonoaminergic function[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Normal rats[2].
Dosage: 3.7-100 µmol/kg.
Administration: s.c., 30 min prior to testing.
Result: Induced dose-dependent and regio-selective alterations in brain monoamine transmission indices and gene expression.
Molecular Weight

213.22

Formula

C₁₁H₁₃F₂NO

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Pirepemat
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