1237540-68-9
Chemical Structure
NC-001
- CAS. Nr.: 1237540-68-9
- Formula:C25H41N7O6
- Molecular Weight:535.64
IUPAC Name: (S)-1-((2-azidoacetyl)-L-alanyl)-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxohexan-2-yl)pyrrolidine-2-carboxamide
InChIKey: HBWASCWOOULSIS-WAMQXFNRSA-N
SMILES: O=C([C@H]1N(C([C@H](C)NC(CN=[N+]=[N-])=O)=O)CCC1)N[C@@H](CCCC)C(N[C@@H](CC(C)C)C([C@]2(C)OC2)=O)=O
Biological Activity: NC-001 is a selective apoptosis inducer targeting renal proximal tubular cells and renal cancer cells. NC-001 inhibits tumor growth in clear cell renal cell carcinoma (CCRCC) xenograft models. NC-001 is promising for research of metastatic renal cell carcinoma[1].
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NC-001 | NC-001 is a selective apoptosis inducer targeting renal proximal tubular cells and renal cancer cells. NC-001 inhibits tumor growth in clear cell renal cell carcinoma (CCRCC) xenograft models. NC-001 is promising for research of metastatic renal cell carcinoma. | |||||||||||||||||||||
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Keywords
