1237541-73-9
1237541-73-9
Chemical Structure
NAB-14
- CAS No.: 1237541-73-9
- Formula:C20H21N3O3
- Molecular Weight:351.40
IUPAC Name: 4-((1H-indol-7-yl)carbamoyl)phenyl diethylcarbamate
InChIKey: WCGIKJOMEYPSIP-UHFFFAOYSA-N
SMILES: O=C(OC1=CC=C(C(NC2=CC=CC3=C2NC=C3)=O)C=C1)N(CC)CC
Biological Activity: NAB-14 is a potent, selective, orally active and non-competitive GluN2C/2D antagonists with an IC50 of 580 nM for GluN1/GluN2D. NAB-14 shows >800-fold selective for recombinant GluN2C and GluN2D over GluN2A and GluN2B. NAB-14 can cross the blood-brain-barrier[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
NAB-14 | 99.44% | NAB-14 is a potent, selective, orally active and non-competitive GluN2C/2D antagonists with an IC50 of 580 nM for GluN1/GluN2D. NAB-14 shows >800-fold selective for recombinant GluN2C and GluN2D over GluN2A and GluN2B. NAB-14 can cross the blood-brain-barrier. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
