1245907-03-2

TC-A 2317 hydrochloride Chemical Structure
1245907-03-2

Chemical Structure

TC-A 2317 hydrochloride

  • CAS No.: 1245907-03-2
  • Formula:C19H29ClN6O
  • Molecular Weight:392.93

IUPAC Name: 2-((6-hydroxy-6-methylheptan-2-yl)amino)-4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)nicotinonitrile hydrochloride

InChIKey: DXVATYHPJJPMIN-UHFFFAOYSA-N

SMILES: N#CC1=C(C)C=C(NC2=NNC(C)=C2)N=C1NC(C)CCCC(C)(O)C.[H]Cl

Biological Activity: TC-A 2317 hydrochloride is an orally active Aurora A kinase inhibitor (Ki=1.2 nM). TC-A 2317 hydrochloride exhibits excellent selectivity to Aurora B kinase (Ki=101 nM) and other 60 kinases, good cell permeability and good PK profile. Antitumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-103266 		TC-A 2317 hydrochloride 99.57% TC-A 2317 hydrochloride is an orally active Aurora A kinase inhibitor (Ki=1.2 nM). TC-A 2317 hydrochloride exhibits excellent selectivity to Aurora B kinase (Ki=101 nM) and other 60 kinases, good cell permeability and good PK profile. Antitumor activity.
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