1245907-03-2
1245907-03-2
Chemical Structure
TC-A 2317 hydrochloride
- CAS No.: 1245907-03-2
- Formula:C19H29ClN6O
- Molecular Weight:392.93
IUPAC Name: 2-((6-hydroxy-6-methylheptan-2-yl)amino)-4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)nicotinonitrile hydrochloride
InChIKey: DXVATYHPJJPMIN-UHFFFAOYSA-N
SMILES: N#CC1=C(C)C=C(NC2=NNC(C)=C2)N=C1NC(C)CCCC(C)(O)C.[H]Cl
Biological Activity: TC-A 2317 hydrochloride is an orally active Aurora A kinase inhibitor (Ki=1.2 nM). TC-A 2317 hydrochloride exhibits excellent selectivity to Aurora B kinase (Ki=101 nM) and other 60 kinases, good cell permeability and good PK profile. Antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TC-A 2317 hydrochloride | 99.57% | TC-A 2317 hydrochloride is an orally active Aurora A kinase inhibitor (Ki=1.2 nM). TC-A 2317 hydrochloride exhibits excellent selectivity to Aurora B kinase (Ki=101 nM) and other 60 kinases, good cell permeability and good PK profile. Antitumor activity. | ||||||||||||||||||||
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Structural Analogs
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HY-10411AZ960 -
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HY-10987AENMD-2076 -
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HY-208737KHK-IN-8 -
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