1246911-78-3
1246911-78-3
Chemical Structure
Velnacrine-d4
Synonym(s): HP 029-d4 free base; Hydroxytacrine-d4
- CAS No.: 1246911-78-3
- Formula:C13H10D4N2O
- Molecular Weight:218.29
IUPAC Name: 9-amino-1,2,3,4-tetrahydroacridin-5,6,7,8-d4-1-ol
InChIKey: HLVVITIHAZBPKB-GYABSUSNSA-N
SMILES: NC1=C2C(CCCC2O)=NC3=C([2H])C([2H])=C([2H])C([2H])=C31
Biological Activity: Velnacrine-d4 is deuterium labeled Velnacrine.
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Velnacrine-d4 | Velnacrine-d4 is deuterium labeled Velnacrine. | |||||||||||||||||||||
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Velnacrine-d4 hydrochloride | 98.60% | Velnacrine-d4 (hydrochloride) is deuterium labeled Velnacrine. | ||||||||||||||||||||
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Velnacrine-d3 maleate | Velnacrine-d3 (maleate) is the deuterium labeled Velnacrine maleate. | |||||||||||||||||||||
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Velnacrine | 98.79% | Velnacrine (HP 029 free base) is an inhibitor for acetylcholinesterase (AChE), with an IC50 of 3.27 μM. Velnacrine reverses the Scopolamine (HY-N0296)-induced amnesia in rat models, and exhibits acute toxicity with LD50 of 65 mg/kg. | ||||||||||||||||||||
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