125251-66-3
Chemical Structure
Arbutamine hydrochloride
- CAS No.: 125251-66-3
- Formula:C18H24ClNO4
- Molecular Weight:353.84
IUPAC Name: (R)-4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butyl)amino)ethyl)benzene-1,2-diol hydrochloride
InChIKey: ATBUNPBAFFCFKY-FERBBOLQSA-N
SMILES: OC1=CC=C([C@@H](O)CNCCCCC2=CC=C(O)C=C2)C=C1O.[H]Cl
Biological Activity: Arbutamine hydrochloride is a short-acting, potent and nonselective β-adrenoceptor agonist. Arbutamine hydrochloride stimulates cardiac β1-, tracheal β2-, and adiopocyte β3- adrenergic receptors. Arbutamine hydrochloride provides cardiac stress increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine hydrochloride can be used for cardiac stress agent [1][2][3].
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Arbutamine hydrochloride | Arbutamine hydrochloride is a short-acting, potent and nonselective β-adrenoceptor agonist. Arbutamine hydrochloride stimulates cardiac β1-, tracheal β2-, and adiopocyte β3- adrenergic receptors. Arbutamine hydrochloride provides cardiac stress increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine hydrochloride can be used for cardiac stress agent . | |||||||||||||||||||||
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References
- [1]. Ruiz M, et al. Arbutamine stress perfusion imaging in dogs with critical coronary artery stenoses: (99m)Tc-sestamibi versus (201)Tl. J Nucl Med. 2002 May;43(5):664-70. [Content Brief]
- [2]. Nagarajan R, et al. A novel catecholamine, arbutamine, for a pharmacological cardiac stress agent. Cardiovasc Drugs Ther. 1996 Mar;10(1):31-8. [Content Brief]
- [3]. Abou-Mohamed G, et, al. Characterization of the adrenergic activity of arbutamine, a novel agent for pharmacological stress testing. Cardiovasc Drugs Ther. 1996 Mar;10(1):39-47. [Content Brief]
