127967-03-7
Chemical Structure
PD 131628
- CAS No.: 127967-03-7
- Formula:C16H17FN4O3
- Molecular Weight:332.33
IUPAC Name: (S)-7-(3-aminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
InChIKey: MUKSDTOOLRNSIO-QMMMGPOBSA-N
SMILES: O=C(O)C1=CN(C2=C(C1=O)C=C(C(N3C[C@H](CC3)N)=N2)F)C4CC4
Biological Activity: PD 131628 is an antimicrobial agent and active PD 131112 metabolite. PD 131628 is two- to four-fold more active than Ciprofloxacin (HY-B0356), inhibiting all strains of Staphylococcus aureus and Streptococcus pneumoniae. PD 131628 is very active against Neisseria spp., Haemophilus influenzae and Moraxella catarrhalis, with MIC90s ranging from 0.004 to 0.008 mg/L[1].
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PD 131628 | PD 131628 is an antimicrobial agent and active PD 131112 metabolite. PD 131628 is two- to four-fold more active than Ciprofloxacin (HY-B0356), inhibiting all strains of Staphylococcus aureus and Streptococcus pneumoniae. PD 131628 is very active against Neisseria spp., Haemophilus influenzae and Moraxella catarrhalis, with MIC90s ranging from 0.004 to 0.008 mg/L. | |||||||||||||||||||||
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Keywords
