128-44-9
Chemical Structure
Saccharin sodium
- CAS No.: 128-44-9
- Formula:C7H4NNaO3S
- Molecular Weight:205.17
IUPAC Name: sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide
InChIKey: WINXNKPZLFISPD-UHFFFAOYSA-M
SMILES: O=C(C1=CC=CC=C12)N([Na])S2(=O)=O
Biological Activity: Saccharin sodium is an orally active, non-caloric artificial sweetener (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties. Saccharin binds to and signals via specific taste receptors, not only in the oral cavity but also alongside the gastrointestinal tract. Saccharin has been reported to bind the human and rodent heteromeric guanine nucleotide-binding protein (G protein) coupled sweet taste receptors T1R2/T2R3 as well as the human bitter taste receptor T2R43 and T2R44. Saccharin can inhibit bacterial growth in vitro[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Saccharin sodium | 99.90% | Saccharin sodium is an orally active, non-caloric artificial sweetener (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties. Saccharin binds to and signals via specific taste receptors, not only in the oral cavity but also alongside the gastrointestinal tract. Saccharin has been reported to bind the human and rodent heteromeric guanine nucleotide-binding protein (G protein) coupled sweet taste receptors T1R2/T2R3 as well as the human bitter taste receptor T2R43 and T2R44. Saccharin can inhibit bacterial growth in vitro. | ||||||||||||||||||||
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Saccharin sodium (Standard) | ≥98% | Saccharin (sodium) (Standard) is the analytical standard of Saccharin (sodium). This product is intended for research and analytical applications. Saccharin sodium is an orally active, non-caloric artificial sweetener (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties. Saccharin binds to and signals via specific taste receptors, not only in the oral cavity but also alongside the gastrointestinal tract. Saccharin has been reported to bind the human and rodent heteromeric guanine nucleotide-binding protein (G protein) coupled sweet taste receptors T1R2/T2R3 as well as the human bitter taste receptor T2R43 and T2R44. Saccharin can inhibit bacterial growth in vitro. | ||||||||||||||||||||
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HLE-IN-1 | HLE-IN-1 (Compound 4) is a human leukocyte elastase HLE inhibitor (Ki=1.8 nM). HLE-IN-1 is used in emphysema and inflammamry pulmonary research. | |||||||||||||||||||||
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Isoindolinone | 99.96% | Isoindolinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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Rivaroxaban impurity 71 | Rivaroxaban impurity 71 (N-Methylphthalimide) is an impurity of Rivaroxaban1. | |||||||||||||||||||||
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4-Methylphthalimide | 99.96% | 4-Methylphthalimide is a stain with biological research applications. | ||||||||||||||||||||
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Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide dihydrate (Standard) | ≥98% | Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide dihydrate (Standard) is the analytical standard of Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide dihydrate. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Saccharin-13C6 | Saccharin-13C6 is the 13C-labeled Saccharin (HY-Y0272). Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties. | |||||||||||||||||||||
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Saccharin | 99.31% | Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties. | ||||||||||||||||||||
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N-Hydroxyphthalimide (Standard) | ≥98% | N-Hydroxyphthalimide (Standard) is the analytical standard of N-Hydroxyphthalimide (HY-Y0396). This product is intended for research and analytical applications. N-Hydroxyphthalimide is a blocking agent and catalyst. N-Hydroxyphthalimide promotes oxidation reactions by generating PINO free radicals and activating hydrogen atom transfer processes. N-Hydroxyphthalimide reduces the expression of anti-apoptotic proteins Survivin and Bcl-xL and activates caspase 9 and caspase 3. N-Hydroxyphthalimide induces Apoptosis. N-Hydroxyphthalimide inhibits the phosphorylation of mTOR (Ser2448, Ser2481) and Akt (Ser473). N-Hydroxyphthalimide has anticancer effects against breast and colon cancer. | ||||||||||||||||||||
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