2. Anti-infection
  3. Bacterial
  4. Saccharin

Saccharin 

Cat. No.: HY-Y0272 Purity: 99.45%
COA Handling Instructions

Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties.

For research use only. We do not sell to patients.

Saccharin Chemical Structure

Saccharin Chemical Structure

CAS No. : 81-07-2

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Saccharin:

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

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Description

Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1].

In Vitro

In vitro, saccharin (0.5, 2.5, 5 mM) inhibits bacterial growth in a species-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo

In vivo, saccharin (oral; 5 mg/kg; twice a day) intake reduces fecal bacterial load and alters microbiome composition, while the intestinal barrier is not obviously affected in male C57BL/6JRj wild type (wt) mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

183.18

Appearance

Solid

Formula

C7H5NO3S
CAS No.
SMILES

O=C(C1=C2C=CC=C1)NS2(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (545.91 mM; Need ultrasonic)

H2O : 2.63 mg/mL (14.36 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4591 mL 27.2956 mL 54.5911 mL
5 mM 1.0918 mL 5.4591 mL 10.9182 mL
10 mM 0.5459 mL 2.7296 mL 5.4591 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (13.65 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (13.65 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (13.65 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Saccharin81-07-2Bacterialoralnon-caloricartificialsweetenersNASbacteriostaticmicrobiomeInhibitorinhibitorinhibit

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