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  3. Bacterial
  4. Saccharin sodium hydrate

Saccharin sodium hydrate 

Cat. No.: HY-B1390B Purity: ≥98.0%
COA Handling Instructions

Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties.

For research use only. We do not sell to patients.

Saccharin sodium hydrate Chemical Structure

Saccharin sodium hydrate Chemical Structure

CAS No. : 82385-42-0

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Free Sample (0.1 - 0.5 mg)   Apply Now  
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
1 g USD 60 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Saccharin sodium hydrate:

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Description

Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties[1].

In Vitro

In vitro, Saccharin sodium hydrate (0.5, 2.5, 5 mM) inhibits bacterial growth in a species-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo

In vivo, Saccharin sodium hydrate (oral; 5 mg/kg; twice a day) intake reduces fecal bacterial load and alters microbiome composition, while the intestinal barrier is not obviously affected in male C57BL/6JRj wild type (wt) mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Appearance

Solid

Formula

C7H5NO3S.xH2O.Na
CAS No.
SMILES

O=C(C1=C2C=CC=C1)N([Na])S2(=O)=O.O.[x]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (Need ultrasonic)

H2O : 83.33 mg/mL (Need ultrasonic)

In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (Infinity mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (Infinity mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (Infinity mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (Infinity mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: ≥98.0%

COA (257 KB) HNMR (184 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Saccharin sodium82385-42-0Bacterialoralnon-caloricartificialsweetenersNASbacteriostaticmicrobiomeInhibitorinhibitorinhibit

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