Saccharin-d4
Based on 1 Customer Validation
Saccharin-d4 is the deuterium labeled Saccharin. Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties.
For research use only. We do not sell to patients.
- Purity: 99.71%
- CAS No.: 1189466-17-8
- Formula: C7HD4NO3S
- Molecular Weight:187.21
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1189466-17-8
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Unlabeled Cas 81-07-2
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Appearance Solid
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Molecular Weight 187.21
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Formula C7HD4NO3S
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Color White to off-white
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SMILES
O=S1(C2=C([2H])C([2H])=C([2H])C([2H])=C2C(N1)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (534.16 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (558 KB)
- English - EN (558 KB)
- Français - FR (558 KB)
- Deutsch - DE (558 KB)
- Norwegian - NO (558 KB)
- Español - ES (558 KB)
- Swedish - SV (558 KB)
- Italian - IT (558 KB)
- Korean - KR (558 KB)
- Portuguese - PT (558 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Sünderhauf A, et al. Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice. Nutrients. 2020 Apr 17;12(4). pii: E1122. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 5.3416 mL | 26.7080 mL | 53.4159 mL | 133.5399 mL |
| 5 mM | 1.0683 mL | 5.3416 mL | 10.6832 mL | 26.7080 mL | |
| 10 mM | 0.5342 mL | 2.6708 mL | 5.3416 mL | 13.3540 mL | |
| 15 mM | 0.3561 mL | 1.7805 mL | 3.5611 mL | 8.9027 mL | |
| 20 mM | 0.2671 mL | 1.3354 mL | 2.6708 mL | 6.6770 mL | |
| 25 mM | 0.2137 mL | 1.0683 mL | 2.1366 mL | 5.3416 mL | |
| 30 mM | 0.1781 mL | 0.8903 mL | 1.7805 mL | 4.4513 mL | |
| 40 mM | 0.1335 mL | 0.6677 mL | 1.3354 mL | 3.3385 mL | |
| 50 mM | 0.1068 mL | 0.5342 mL | 1.0683 mL | 2.6708 mL | |
| 60 mM | 0.0890 mL | 0.4451 mL | 0.8903 mL | 2.2257 mL | |
| 80 mM | 0.0668 mL | 0.3338 mL | 0.6677 mL | 1.6692 mL | |
| 100 mM | 0.0534 mL | 0.2671 mL | 0.5342 mL | 1.3354 mL |
Saccharin-d4 Related Classifications
HY-Y0272S Related Classifications
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