1287128-95-3
1287128-95-3
Chemical Structure
LIMK2-IN-1
- CAS. Nr.: 1287128-95-3
- Formula:C21H20N2O3S
- Molecular Weight:380.46
InChIKey: UNWYGJWQCPQFQS-UHFFFAOYSA-N
SMILES: CN(C(C1=CC=C(S(=O)(NC2=CC=CC=C2)=O)C=C1)=O)CC3=CC=CC=C3
Biological Activity: LIMK2-IN-1 is a LIMK2 inhibitor (IC50 = 0.039 μM) that binds the DFG-out hydrophobic pocket in an allosteric, non-ATP-competitive manner without interacting with the hinge region, and is highly selective relative to representative kinases and LIMK1. LIMK2-IN-1 can be used for LIMK2-related research[1].
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LIMK2-IN-1 | LIMK2-IN-1 is a LIMK2 inhibitor (IC50 = 0.039 μM) that binds the DFG-out hydrophobic pocket in an allosteric, non-ATP-competitive manner without interacting with the hinge region, and is highly selective relative to representative kinases and LIMK1. LIMK2-IN-1 can be used for LIMK2-related research. | |||||||||||||||||||||
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