128831-46-9
Chemical Structure
TMP-153
- CAS No.: 128831-46-9
- Formula:C24H18ClF2N3O
- Molecular Weight:437.87
IUPAC Name: 1-(4-(2-chlorophenyl)-6,7-dimethylquinolin-3-yl)-3-(2,4-difluorophenyl)urea
InChIKey: FFKNNBNIAHVVCU-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(F)C=C1F)NC2=C(C3=CC=CC=C3Cl)C4=CC(C)=C(C)C=C4N=C2
Biological Activity: TMP-153 is an orally active inhibitor of ACAT with an IC50 value of approximately 5-10 nM against hepatic and intestinal ACAT in varicose animals. TMP-153 exhibits cholesterol-lowering effects and can be utilized in the research of atherosclerosis[1].
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TMP-153 | 99.34% | TMP-153 is an orally active inhibitor of ACAT with an IC50 value of approximately 5-10 nM against hepatic and intestinal ACAT in varicose animals. TMP-153 exhibits cholesterol-lowering effects and can be utilized in the research of atherosclerosis. | ||||||||||||||||||||
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Keywords