1292290-38-0
Chemical Structure
LY2881835
- CAS No.: 1292290-38-0
- Formula:C33H33NO3
- Molecular Weight:491.62
IUPAC Name: (S)-3-(4-((4-(spiro[indene-1,4'-piperidin]-1'-ylmethyl)benzyl)oxy)phenyl)hex-4-ynoic acid
InChIKey: FHRWHNJJQGSCQC-LJAQVGFWSA-N
SMILES: OC(C[C@H](C#CC)C(C=C1)=CC=C1OCC(C=C2)=CC=C2CN3CCC4(CC3)C5=CC=CC=C5C=C4)=O
Biological Activity: LY2881835 is a potent and selective agonist of G protein-coupled receptor 40 (GPR40). LY2881835 has efficacious and durable dose-dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion. LY2881835 has the potential for the research of type 2 diabetes mellitus[1]. LY2881835 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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LY2881835 | LY2881835 is a potent and selective agonist of G protein-coupled receptor 40 (GPR40). LY2881835 has efficacious and durable dose-dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion. LY2881835 has the potential for the research of type 2 diabetes mellitus. LY2881835 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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