129280-34-8
129280-34-8
Chemical Structure
Isoangustone A
- CAS No.: 129280-34-8
- Formula:C25H26O6
- Molecular Weight:422.47
IUPAC Name: 3-(3,4-dihydroxy-5-(3-methylbut-2-en-1-yl)phenyl)-5,7-dihydroxy-6-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
InChIKey: QNLGNISMYMFVHP-UHFFFAOYSA-N
SMILES: O=C1C2=C(O)C(C/C=C(C)/C)=C(O)C=C2OC=C1C3=CC(C/C=C(C)/C)=C(O)C(O)=C3
Biological Activity: Isoangustone A is an anticancer and anti-inflammatory agent. Isoangustone A induces cancer cells apoptosis and autophagic cell death[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Isoangustone A | 96.0% | Isoangustone A is an anticancer and anti-inflammatory agent. Isoangustone A induces cancer cells apoptosis and autophagic cell death. | ||||||||||||||||||||
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References
- [1]. Song NR, et al. Isoangustone A, a novel licorice compound, inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Cancer Prev Res (Phila). 2013 Dec;6(12):1293-303. [Content Brief]
- [2]. Tang S, et al. Isoangustone A induces autophagic cell death in colorectal cancer cells by activating AMPK signaling. Fitoterapia. 2021 Jul;152:104935. [Content Brief]
- [3]. Li J, et al. Isoangustone A suppresses mesangial fibrosis and inflammation in human renal mesangial cells. Exp Biol Med (Maywood). 2011 Apr 1;236(4):435-44. [Content Brief]
Keywords
