129622-68-0
Chemical Structure
(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat)
- CAS No.: 129622-68-0
- Formula:C162H254N50O36
- Molecular Weight:3478.06
SMILES: NC([C@H](C)NC([C@H]([C@H](O)C)NC([C@H](CC1=CN=CN1)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC([C@H](CC2=CN=CN2)NC([C@H](CC3=CN=CN3)NC([C@H](CC(C)C)NC([C@H](CC4=CC=CC=C4)NC([C@H](CC5=CC=CC=C5)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@@H](NC([C@H](CC(C)C)NC([C@@H](N)CC(C)C)=O)=O)CC6=CN=CN6)=O)=O)=O)CC7=CNC8=CC=CC=C78)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent PTH-1R antagonist and does not display any partial agonist activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) | 99.77% | (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent PTH-1R antagonist and does not display any partial agonist activity. | ||||||||||||||||||||
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- [1]. Nutt RF, et al. Removal of partial agonism from parathyroid hormone (PTH)-related protein-(7-34)NH2 by substitution of PTH amino acids at positions 10 and 11. Endocrinology. 1990 Jul;127(1):491-3. [Content Brief]
- [2]. Portal-Núñez S, et al. Parathyroid hormone-related protein exhibits antioxidant features in osteoblastic cells through its N-terminal and osteostatin domains. Bone Joint Res. 2018 Jan;7(1):58-68. [Content Brief]
